Favipiravir CAS NO.259793-96-9

Anqing World Chemical Co.,Ltd.Mainly responsible for the development of domestic and international business.In 2015,Haikang established the second branch,called Anqing Xuanyu Medical&Technology Co., Ltd, it is an R&D company that selects reliable technology and cooperative research partner for our corporation.

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Favipiravir, whose chemical name is 6-fluoro-3-hydroxypyrazine-2-carboxamide, is a new broad-spectrum antibody targeting RNAChemicalbook-dependent RNA polymerase (RdRp) developed by Japan’s Toyama Chemical Pharmaceutical Company Viral drugs, approved for marketing in Japan in March 2014, are used to treat new and recurrent influenza.

Favipiravir (favipiravir), chemically named 6-fluoro-3-hydroxypyrazine-2-carboxamide, is a new broad-spectrum antibody targeting RNA-dependent RNA polymerase (RdRp) developed by Japan’s Toyama Chemical Pharmaceutical Company Viral drugs, approved for marketing in the Japanese Chemicalbook in March 2014, are used to treat new and recurrent influenza. During the outbreak of the new coronavirus, the results of the Phase I clinical study of the drug released in March 2020 showed that the drug may have the effect of speeding up virus clearance and alleviating the progress of new coronavirus pneumonia.

Favipiravir exhibits anti-influenza virus activity. The IC50 ranges for influenza A virus, influenza B virus and influenza C virus are 0.013-0.48μg/ml, 0.039-0.089μg/ml, and 0.030-0.057μg/ml, respectively. In mammalian cell lines (MDCK cells, ChemicalbookVero cells, HEL cells, A549 cells, HeLa cells, and HEp-2 cells), Favipiravir at a concentration of up to 1,000 μg/ml showed no toxicity. Favipiravir induced lethal mutations in MDCK cells inoculated with seasonal influenza A (H1N1) virus.