ectoine API CAS NO.96702-03-3

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The chemical formula of Ectoine is 2-methyl-1,4,5,6,-tetrahydropyrimidine-4-carboxylic acid, also known as tetrahydropyrimidine, which is a new type of water-soluble amphoteric discovered in 1985 Ionic amino acid derivatives. In 1985, Galin Chemicalbookski used nuclear magnetic resonance and mass spectrometry to identify and isolate ectoine in halophilic bacteria for the first time. At high salt concentrations, Ectoine acts as an osmotic pressure compensation solute to accumulate in some halophilic bacteria to resist the high osmotic pressure of the external environment.Ectoine is a natural and effective cosmetic active ingredient. Because it has a wide range of cell protection functions, it can be used in a variety of cosmetics with different functions. Ectoine has the functions of moisturizing, anti-oxidation, protection against photo-aging and sun protection. Good moisture retention. Pretreating the skin with Ectoine can reduce skin damage caused by dehydration; one molecule of Ectoine can complex four or five water molecules, which can structure free water in cells. Compared with glycerin, ectoine is more moisturizing to the skin. Relevant data shows that during the application period of Ectoine, the skin's moisture retention capacity can be continuously improved, and the skin's water retention capacity will not decrease immediately after deactivation, and the skin's water retention capacity is still higher than the control group after one week of deactivation. Antioxidant effect Clinical trials have shown that ectoine can prevent the weakening of the antioxidant capacity of cells with the increase of age, and has a certain antioxidant capacity. Experimental data shows: 0.1mMEctoine, 0.5mM thioine and 1.5mM mannitol mixed to use in Chemicalbook, can reduce human glial cell DNA single-strand breaks under 400-800nm light source, reduce the intensity of ROS oxidation reaction, thereby reducing light to the skin Of oxidative damage. Protection of the immune system Langerhanscells in the epidermis play a key role in the skin's immune system, but they are very sensitive to UV pressure. And Ectoine can just prevent the number of Langerhans cells from being reduced by ultraviolet radiation, so that the skin's immune system can maintain normal functioning. Protection against photo-aging and sunscreen The aging of the skin is not only the result of the passage of time, but one of the important external factors is ultraviolet light, especially UVA (320-400nm). In the entire ultraviolet band, UVA has the longest wavelength and the lowest energy, but unlike UVB, the change in UVA content in the sun is affected little by latitude, time period, weather and season, so the UVA exposure received every day and year The dose is almost fixed and accumulates in large quantities continuously throughout our lives.