oseltamivir phosphate CAS NO.204255-11-8

Anqing World Chemical Co.,Ltd.Mainly responsible for the development of domestic and international business.In 2015,Haikang established the second branch,called Anqing Xuanyu Medical&Technology Co., Ltd, it is an R&D company that selects reliable technology and cooperative research partner for our corporation.

Haikang is committed to R&D,manufacture and sales of chemical raw materials API and intermediates.Meanwhile,we also provide services like product customization,process improvement,achievement transfer, etc. Through years effort,Haikang has made remarkable achievements in the R&D and production of anti-virus,antidiabetic,antineoplastic,beauty and whitening resist oxidation series API and intermediates.The main products are Ganciclovir, Sitagliptin, Vildagliptin, Silodosin and Imatinib API and Intermediates.

To deal with increasingly competition,Haikang adheres to “Customer is First,Technology is Leading,Quality is Life,Honesty for Developing”,and optimizes actively the products and better service to customers.

Oseltamivir phosphate is an anti-influenza virus drug, the trade name is Tamiflu (Tamiflu), the appearance is white to yellowish white powder, can be divided into type A (type A) and type B (type B) influenza virus nerve ammonia The selective inhibitor of acid enzyme prevents the virus from being released and spread from infected cells by inhibiting the neuraminidase of the virus, thereby achieving the purpose of controlling flu symptoms. It is clinically used for the treatment of influenza A and B in adults and children aged 1 and over, and the prevention of influenza A and B in adults and adolescents aged 13 and over. Oseltamivir phosphate is rapidly metabolized to oseltamivir carboxyl Chemicalbook after being absorbed by the gastrointestinal tract. At least 75% of the oral dose is involved in the system circulation in the form of oseltamivir carboxylate. The drug is active The ingredient is a potent and unique neuraminidase inhibitor that acts on all links of influenza virus infection and prevents the replication of all clinically relevant influenza virus A strains or B strains. There is an inhibitory effect in vitro at a very low nanomolecular concentration. The active metabolite was observed to inhibit the growth of influenza virus in vitro, and it was also observed to inhibit the replication and pathogenicity of influenza virus in vivo. This product reduces the spread of influenza A or B viruses by inhibiting the release of viruses from infected cells.

Oseltamivir phosphate is a prodrug of its active metabolite, and its active metabolite (oseltamivir carboxylate) is a selective influenza virus neuraminidase inhibitor. Neuraminidase is a glycoprotease on the surface of the virus. Its activity is essential for the release of newly formed virus particles from infected cells and the further spread of infectious virus in the human body. The active metabolites of this product can inhibit the neuraminidase activity of A Chemicalbook and B influenza viruses. The half inhibitory concentration of viral neuraminidase activity in vitro is as low as nanograms (ng). The active metabolite was observed to inhibit the growth of influenza virus in vitro, and it was also observed to inhibit the replication and pathogenicity of influenza virus in vivo. This product reduces the spread of influenza A or B viruses by inhibiting the release of viruses from infected cells.