Valaciclovir hydrochloride API CAS NO.124832-27-5

Anqing World Chemical Co.,Ltd.Mainly responsible for the development of domestic and international business.In 2015,Haikang established the second branch,called Anqing Xuanyu Medical&Technology Co., Ltd, it is an R&D company that selects reliable technology and cooperative research partner for our corporation.

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The chemical name of valacyclovir hydrochloride is: L-valine-2-[(6-oxo-2-amino-1,6-dihydro-9H-purin-9-yl) methoxy] ethyl ester salt The acid salt, valacyclovir hydrochloride is the L-valine ester of acyclovir and the prodrug of acyclovir. After entering the body, it is immediately hydrolyzed into acyclovir to exert its efficacy. It is used to treat varicella-zoster and infections caused by type I and type II herpes simplex Chemicalbook virus, including initial and recurrent genital herpes virus infections. Action Valacyclovir hydrochloride hydrate is the L-valine ester of acyclovir and the prodrug of acyclovir. After entering the body, it is immediately hydrolyzed into acyclovir to exert its efficacy. It is used for the treatment of varicella-zoster and infections caused by type I and type II herpes simplex virus, including initial and recurrent genital herpes virus infections.

Valacyclovir hydrochloride hydrate is the L-valine ester of acyclovir and the prodrug of acyclovir. After entering the body, it is immediately hydrolyzed into acyclovir to exert its efficacy. It is used for the treatment of varicella-zoster and infections caused by type I and type II herpes simplex virus, including initial and recurrent genital herpes virus infections.

After oral administration of valacyclovir hydrochloride hydrate, it is hydrolyzed into acyclovir in the body. After acyclovir enters herpes virus-infected cells, it competes with deoxynucleosides for viral thymokinase or cell kinase, and the drug is phosphorylated into an activated form Acyclovir triphosphate, then inhibits viral replication by Chemicalbook in two ways: one is to interfere with viral DNA polymerase and inhibit viral replication; the other is to bind to the growing DNA chain under the action of DNA polymerase to cause DNA chain extension Interrupted. The antiviral activity of valacyclovir hydrochloride is better than that of acyclovir, and its metabolites do not accumulate in the body.